Sodium Polystyrene Sulfate

Sodium Polystyrene Sulfate Ingredients: Sodium Polystyrene Sulfate
Representative Names: Kayexalate, Kionex

What is Sodium Polystyrene Sulfate powder ?

Sodium Polystyrene Sulfate treats a condition called hyperkalemia, in which there is too much potassium in the body (blood). Sodium Polystyrene Sulfate is an ion-exchange resin that loses sodium ions, that are replaced by potassium ions. Sodium Polystyrene Sulfate powder can be made into an oral suspension (to be taken by mouth) or into an enema (for rectal use). Generic Sodium Polystyrene Sulfate powder is available.

What should my health care professional know before I take Sodium Polystyrene Sulfate ?

They need to know if you have any of these conditions:
•constipation or a stomach or bowel obstruction
•frequent use of laxatives
•low levels of calcium or potassium in the blood
•restricted sodium diet
•an unusual or allergic reaction to Sodium Polystyrene Sulfate, other medicines, foods, dyes, or preservatives
•pregnant or trying to get pregnant
•breast-feeding

How should I take Sodium Polystyrene Sulfate ?

Sodium Polystyrene Sulfate powder is not usually for self-administration. It may be given in a hospital or clinic setting. For oral (by mouth) use, Sodium Polystyrene Sulfate powder is mixed with a small quantity of water. The amount of water depends on the dose given and can range from 20 to 100 ml (about half an ounce to three ounces). The suspension must be freshly prepared and should not be stored for more than 24 hours. Alternatively a suspension of Sodium Polystyrene Sulfate can be given as an enema (into the rectum). Follow the directions on the prescription label. Take your medicine as directed. Do not take more often than directed.

Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.

What if I miss a Sodium Polystyrene Sulfate dose ?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What drug(s) may interact with Sodium Polystyrene Sulfate ?

•antacids
•calcium salts
•heart medicine
•insulin
•sodium bicarbonate
•sorbitol
•water pills

Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines.

What side effects may I notice from taking Sodium Polystyrene Sulfate ?

Side effects that you should report to your prescriber or health care professional as soon as possible:
•confusion
•depression. irritability
•difficulty breathing, shortness of breath
•increased thirst
•irregular heartbeat, or chest pain
•muscle spasms or muscle cramps
•passing large amounts of urine
•rectal or lower stomach pain
•severe constipation or diarrhea
•unusual swelling or water retention
•unusual weakness

Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome):
•mild constipation or diarrhea
•loss of appetite
•nausea, vomiting

What should I watch for while taking Sodium Polystyrene Sulfate ?

Sodium Polystyrene Sulfate can affect the balance of many salts and water in your body, and these can affect normal working of the heart. Patients receiving Sodium Polystyrene Sulfate should be carefully monitored for changes in salt levels in the blood and for heart problems.

Elderly patients are more susceptible to the effects of constipation induced by Sodium Polystyrene Sulfate. Do not treat constipation yourself; call your prescriber or health care professional for advice.

Patients on sodium-restricted diets should take Sodium Polystyrene Sulfate with caution. You will also need to follow a low-potassium diet to prevent additional problems. Discuss dietary recommendations with your prescriber or health care professional, and follow these carefully.

Where can I keep Sodium Polystyrene Sulfate ?

Keep out of the reach of children.

Store the dry powder at room temperature, between 15 and 30 degrees C (59—86 degrees F). After mixing the suspension, use within 24 hours. Throw away any unused suspension. Throw away unused powder after the expiration date.