|
Not all patients with anxiety require treatment,
but for more severe cases, treatment is recommended. Because anxiety
often has more than one cause and is experienced in highly
individual ways, its treatment usually requires more than one type
of therapy. In addition, there is no way to tell in advance how
patients will respond to a specific drug or therapy. Sometimes the
doctor will need to try different medications or methods of
treatment before finding the best combination for the particular
patient. It usually takes about six to eight weeks for the doctor to
evaluate the effectiveness of a treatment regimen.
Medications
Medications are often prescribed to relieve the
physical and psychological symptoms of anxiety. Most agents work by
counteracting the biochemical and muscular changes involved in the
fight-or-flight reaction. Some work directly on the chemicals in the
brain that are thought to underlie the anxiety.
ANXIOLYTICS
Anxiolytics are sometimes called tranquilizers.
Most anxiolytic drugs are either benzodiazepines or barbiturates.
Barbiturates, once commonly used, are now rarely used in clinical
practice. Barbiturates work by slowing down the transmission of
nerve impulses from the brain to other parts of the body. They
include such drugs as phenobarbital (Luminal) and pentobarbital (Nembutal).
Benzodiazepines work by relaxing the skeletal muscles and calming
the limbic system. They include such drugs as chlordiazepoxide (Librium)
and diazepam (Valium). Both barbiturates and benzodiazepines are
potentially habit-forming and may cause withdrawal symptoms, but
benzodiazepines are far less likely than barbiturates to cause
physical dependency. Both drugs also increase the effects of alcohol
and should never be taken in combination with it.
Two other types of anxiolytic medications include
meprobamate (Equanil), which is now rarely used, and buspirone (BuSpar),
a new type of anxiolytic that appears to work by increasing the
efficiency of the body's own emotion-regulating brain chemicals.
Buspirone has several advantages over other anxiolytics. It does not
cause dependence problems, does not interact with alcohol, and does
not affect the patient's ability to drive or operate machinery.
However, buspirone is not effective against certain types of anxiety,
such as panic disorder.
ANTIDEPRESSANTS AND BETA-BLOCKERS
For some anxiety disorders, such as obsessive-compulsive
disorder and panic type anxiety, a type of drugs used to treat
depression, selective serotonin reuptake inhibitors (SSRIs; such as
Prozac and Paxil), are the treatment of choice. Because anxiety
often coexists with symptoms of depression, many doctors prescribe
antidepressant medications for anxious/depressed patients. While
SSRIs are more common, antidepressants are sometimes prescribed,
including tricyclic antidepressants such as imipramine (Tofranil) or
monoamine oxidase inhibitors (MAO inhibitors) such as phenelzine (Nardil).
Beta-blockers are medications that work by
blocking the body's reaction to the stress hormones that are
released during the fight-or-flight reaction. They include drugs
like propranolol (Inderal) or atenolol (Tenormin). Beta-blockers are
sometimes given to patients with post-traumatic anxiety symptoms.
More commonly, the beta-blockers are given to patients with a mild
form of social phobic anxiety, such as fear of public speaking.
Psychotherapy
Most patients with anxiety will be given some
form of psychotherapy along with medications. Many patients benefit
from insight-oriented therapies, which are designed to help them
uncover unconscious conflicts and defense mechanisms in order to
understand how their symptoms developed. Patients who are extremely
anxious may benefit from supportive psychotherapy, which aims at
symptom reduction rather than personality restructuring.
Two newer approaches that work well with anxious
patients are cognitive-behavioral therapy (CBT), and relaxation
training. In CBT, the patient is taught to identify the thoughts and
situations that stimulate his or her anxiety, and to view them more
realistically. In the behavioral part of the program, the patient is
exposed to the anxiety-provoking object, situation, or internal
stimulus (like a rapid heart beat) in gradual stages until he or she
is desensitized to it. Relaxation training, which is sometimes
called anxiety management training, includes breathing exercises and
similar techniques intended to help the patient prevent
hyperventilation and relieve the muscle tension associated with the
fight-or-flight reaction. Both CBT and relaxation training can be
used in group therapy as well as individual treatment. In addition
to CBT, support groups are often helpful to anxious patients,
because they provide a social network and lessen the embarrassment
that often accompanies anxiety symptoms.
Psychosurgery
Surgery on the brain is very rarely recommended
for patients with anxiety; however, some patients with severe cases
of obsessive- compulsive disorder (OCD) have been helped by an
operation on a part of the brain that is involved in OCD. Normally,
this operation is attempted after all other treatments have failed. |