Treatment choices for skin angiomas and
vascular malformations depend on their type, location, and severity,
and whether they cause symptoms, pain, or disfigurement.
Watchful waiting
No treatment is given, but the mark is regularly examined. This
continues until the mark disappears, or requires treatment. This
approach is particularly appropriate for the treatment of
hemangiomas, which often do not require treatment, since they
eventually shrink by themselves.
Drugs
Corticosteroids
Daily doses of the anti-inflammatory drugs prednisone or
prednisolone are given for up to 2 months with gradual reduction of
the dose. The marks begin to subside within 7-10 days, but may take
up to 2 months to fully disappear. If no response is seen in 2 weeks,
the drug is discontinued. Treatment may be repeated. Side effects
include growth retardation, increased blood pressure and blood sugar,
cataracts, glandular disorders, and infection. The corticosteroids
triamcinolone acetate and betamethasone sodium phosphate or acetate
are injected directly into the marks with a response usually
achieved within a week; additional injections are given in 4-6 weeks.
Side effects include tissue damage at the injection site.
Interferon Alpha-2a
This drug reduces cell growth, and is used for vascular marks that
affect vision, and that are unresponsive to corticosteroids. Given
in daily injections under the skin, a response rate of 50% is
achieved after about 7 months. Side effects include fever, chills,
muscle and joint pain, vision disorders, low white and red blood
cell counts, fatigue, elevated liver enzymes, nausea, blood clotting
problems, and nerve damage.
Antibiotics
Oral or topical (applied to the skin) antibiotics are prescribed for
infected marks.
Surgery
Laser surgery
Lasers create intense heat that destroys abnormal blood vessels
beneath the skin, without damaging normal skin. Two types of lasers
are used: the flashlamp-pulsed dye laser (FPDL) and the
neodymium:YAG (Nd:YAG) laser. The FPDL, used mainly for strawberry
marks and port-wine stains, penetrates to a depth of 1.8 mm and
causes little scarring, while the Nd:YAG laser penetrates to a depth
of 6 mm, and is used to treat deep hemangiomas. Laser surgery is not
usually painful, but can be uncomfortable. Anesthetic cream is used
for FPDL treatment. Treatment with the Nd:YAG laser requires local
or general anesthesia. Children are usually sedated or anesthetized.
Healing occurs within 2 weeks. Side effects include bruising, skin
discoloration, swelling, crusting, and minor bleeding.
Surgical excision
Under local or general anesthesia, the skin is cut with a surgical
instrument, and vascular marks or their scars are removed. The cut
is repaired with stitches or skin clips.
Cryosurgery
Vascular marks are frozen with an extremely cold substance sprayed
onto the skin. Wounds heal with minimal scarring.
Electrodesiccation
Affected vessels are destroyed with the current from an electric
needle.
Other treatments
These include:
Sclerotherapy. Injection of a special solution causes blood clotting
and shrinkage with little scarring. Side effects include stinging,
swelling, bruising, scarring, muscle cramping, and allergic
reactions. This treatment is used most commonly for spider angiomas.
Embolization. Material injected into the vessel blocks blood flow
which helps control blood loss during or reduces the size of
inoperable growths. A serious side effect, stroke, can occur if a
major blood vessel becomes blocked.
Make-up. Special brands are designed to cover birthmarks (Covermark
or Dermablend).
Cleaning and compression. Bleeding marks are cleaned with soap and
water or hydrogen peroxide, and compressed with a sterile bandage
for 5-10 minutes.
Alternative treatment
Alternative treatments for strengthening weak blood vessels include
eating high-fiber foods and those containing bioflavonoids,
including citrus fruit, blueberries, and cherries, supplementing the
diet with vitamin C, and taking the herbs, ginkgo (Ginkgo biloba)
and bilberry (Vaccinium myrtillus.) |