BRONCHIECTASIS SYMPTOMS |
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Prior to the widespread use of
immunizations, bronchiectasis was often the result of a serious
infection with either measles or whooping cough. Currently, viruses
that cause influenza (flu) or influenza-like syndromes, as well as a
number of bacteria may precede the development of bronchiectasis.
Patients who have been infected with tuberculosis or the virus which
causes AIDS (HIV or human immunodeficiency virus) also have an
increased chance of bronchiectasis.
A number of pre-existing conditions may cause an individual to be
more susceptible than normal to infection, with increased risk of
bronchiectasis developing. These conditions include disorders of
cilia, and immune disorders.
Cilia are the tiny hairs which usually line the bronchial tubes.
Cilia wave constantly, sweeping the bronchial tubes clean of
bacterial or viral invaders, and cleaning away excess secretions
(mucus, sputum) which may be produced by the bronchi. When these
cilia are abnormal or absent at birth, various bacterial or viral
invaders may remain in the respiratory tract, multiply, and cause
serious infections.
Immune disorders include decreased production of certain immune
chemicals (immunoglobulins) which usually serve to fight off
infection by bacterial or viral invasion. When these immunoglobulins
are not produced in large enough quantity, bacterial and viral
invaders are not effectively killed off, and infection occurs.
Other causes of bronchiectasis include an abnormally blocked (obstructed)
airway. This can be due to tumor growth within the bronchial tube,
or due to a child accidentally inhaling a small object which then
blocks off the bronchial tube. People with the disease called cystic
fibrosis (CF) often have their bronchial tubes obstructed by the
thick, sticky mucus which is a hallmark of CF. Toxic exposures (breathing
ammonia, for example) can harm the bronchi, and lead to
bronchiectasis. An extreme allergic response of the immune system to
the presence of certain fungi (especially one called Aspergillus)
can also damage the bronchial tubes enough to result in
bronchiectasis.
Symptoms of bronchiectasis include constant cough and the production
of infected sputum (sputum is a mixture of mucus and pus), which may
be bloody. In some cases, there may be wheezing and shortness of
breath. The constant, low-level of infection may flare, resulting in
increased production of sputum, worsening of the cough, and fever.
The area of the lung served by the affected bronchial tube may
become severely infected, resulting in pneumonia. |
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