CHRONIC OBSTRUCTIVE LUNG DISEASE SYMPTOMS |
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There are several important risk factors
for COPD:
Lifestyle. Cigarette smoking is by far the most important risk
factor for COPD (80% of all cases). Cigar and pipe smoking can also
cause COPD. Air pollution and industrial dusts and fumes are other
important risk factors.
Age. Chronic bronchitis is more common in people over 40 years old;
emphysema occurs more often in people 65 years of age and older.
Socioeconomic class. COPD-related deaths are about twice as high
among unskilled and semi-skilled laborers as among professionals.
Family clustering. It is thought that heredity predisposes people in
certain families to the development of COPD when other causes, such
as smoking and air pollution, are present.
Lung infections. Lung infections make all forms of COPD worse.
In the general population, emphysema usually develops in older
individuals with a long smoking history. However, there is also a
form of emphysema that runs in families. People with this type of
emphysema have a hereditary deficiency of a blood component, an
enzyme inhibitor called alpha-1-antitrypsin (AAT). This type of
emphysema is sometimes called "early onset emphysema" because it can
appear when a person is as young as 30 or 40 years old. It is
estimated that there are between 75,000 and 150,000 Americans who
were born with AAT-deficiency. Of this group, emphysema afflicts an
estimated 20,000-40,000 people (1-3% of all cases of emphysema). The
risk of developing emphysema for an AAT-deficient individual who
also smokes is much greater than for others.
The first symptoms of chronic bronchitis are cough and mucus
production. These symptoms resemble a chest cold that lingers on for
weeks. Later, shortness of breath develops. Cough, sputum
production, and shortness of breath may become worse if a person
develops a lung infection. A person with chronic bronchitis may
later develop emphysema as well. In emphysema, shortness of breath
on exertion is the predominant early symptom. Coughing is usually
minor and there is little sputum. As the disease progresses, the
shortness of breath occurs with less exertion, and eventually may be
present even when at rest. At this point, a sputum producing cough
may also occur. Either chronic bronchitis or emphysema may lead to
respiratory failure--a condition in which there occurs a dangerously
low level of oxygen or a serious excess of carbon dioxide in the
blood. |
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| CHRONIC OBSTRUCTIVE LUNG DISEASE RELATED ITEMS |
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