CORONARY ARTERY DISEASE
TREATMENTS |
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Coronary artery disease can be treated
many ways. The choice of treatment depends on the severity of the
disease. Treatments include lifestyle changes and drug therapy,
percutaneous transluminal coronary angioplasty, and coronary artery
bypass surgery. Coronary artery disease is a chronic disease
requiring lifelong care. Angioplasty or bypass surgery is not a
"cure."
People with less severe coronary artery disease may gain adequate
control through lifestyle changes and drug therapy. Many of the
lifestyle changes that prevent disease progression--a low-fat, low-cholesterol
diet, weight loss if needed, exercise, and not smoking--also help
prevent the disease from developing. These lifestyle changes are
discussed in more detail under prevention.
Drugs such as nitrates, beta-blockers, and calcium-channel blockers
relieve chest pain and complications of coronary artery disease, but
they cannot clear blocked arteries. Nitrates (nitroglycerin) improve
blood flow to the heart. Beta-blockers (acebutelol, propranolol)
reduce the amount of oxygen required by the heart during stress. One
type of calcium-channel blocker (verapamil, diltiazem hydrochloride)
helps keep the arteries open and reduces blood pressure. Aspirin
helps prevent blood clots from forming on plaques, reducing the
likelihood of a heart attack. Cholesterol-lowering medications are
also indicated in most cases.
Percutaneous transluminal coronary angioplasty and bypass surgery
are procedures that enter the body (invasive procedures) to improve
blood flow in the coronary arteries. Percutaneous transluminal
coronary angioplasty, usually called coronary angioplasty, is a non-surgical
procedure. A catheter tipped with a balloon is threaded from a blood
vessel in the thigh into the blocked artery. The balloon is inflated,
compressing the plaque to enlarge the blood vessel and open the
blocked artery. The balloon is deflated, and the catheter is
removed. Coronary angioplasty is performed by a cardiologist in a
hospital and generally requires a stay of one or two days. Coronary
angioplasty is successful about 90% of the time, but for one-third
of patients the artery narrows again within six months. The
procedure can be repeated. It is less invasive and less expensive
than coronary artery bypass surgery.
In coronary artery bypass surgery, a healthy artery or vein from an
arm, leg, or chest wall is used to build a detour around the
coronary artery blockage. The healthy vessel then supplies oxygen-rich
blood to the heart. Bypass surgery is major surgery. It is
appropriate for those patients with blockages in two or three major
coronary arteries, those with severely narrowed left main coronary
arteries, and those who have not responded to other treatments. It
is performed in a hospital under general anesthesia. A heart-lung
machine is used to support the patient while the healthy vein or
artery is attached past the blockage to the coronary artery. About
70% of patients who have bypass surgery experience full relief from
angina; about 20% experience partial relief. Only about 3-4% of
patients per year experience a return of symptoms. Survival rates
after bypass surgery decrease over time. At five years after surgery,
survival expectancy is 90%; at 10 years about 80%, at 15 years about
55%, and at 20 years about 40%.
Three semi-experimental surgical procedures for unblocking coronary
arteries are currently being studied. Atherectomy is a procedure in
which the cardiologist shaves off and removes strips of plaque from
the blocked artery. In laser angioplasty, a catheter with a laser
tip is inserted into the affected artery to burn or break down the
plaque. A metal coil called a stent can be implanted permanently to
keep a blocked artery open. Stenting is becoming more common.
Alternative treatment
Natural therapies may reduce the risk of certain types of heart
disease, but once symptoms appear, conventional medical attention is
necessary. A healthy diet (including cold water fish as a source of
essential fatty acids) and exercise, important components of
conventional prevention and treatment strategies, also are
emphasized in alternative approaches to coronary artery disease.
Herbal medicine has a variety of remedies that may have a beneficial
effect on coronary artery disease. For example, ginger (Zingiber
officinale) may help reduce cholesterol. Garlic (Allium sativum),
ginger, and hot red or chili peppers are all circulatory enhancers
that can help prevent blood clots. Yoga and other bodywork, massage,
relaxation therapies, and talking therapies may also help prevent
coronary artery disease and stop, or even reverse, the progression
of atherosclerosis. Vitamin and mineral therapy to reduce, reverse,
or protect against coronary artery disease includes chromium;
calcium and magnesium; B-complex vitamins; the anti-oxidant vitamins
C and E; selenium; and zinc. Traditional Chinese medicine may
recommend herbal remedies, massage, acupuncture, and dietary
modification. |
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