EMBOLISM
DEFINITION |
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An embolism is an obstruction in a blood vessel
due to a blood clot or other foreign matter that gets stuck while
traveling through the bloodstream. The plural of embolism is emboli. |
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Emboli have moved from the place where they were formed through the
bloodstream to another part of the body, where they obstruct an
artery and block the flow of blood. The emboli are usually formed
from blood clots but are occasionally comprised of air, fat, or
tumor tissue. Embolic events can be multiple and small, or single
and massive. They can be life-threatening and require immediate
emergency medical care. There are three general categories of emboli:
arterial, gas, and pulmonary. Pulmonary emboli are the most common.
Arterial embolism
In arterial emboli, blood flow is blocked at the junction of major
arteries, most often at the groin, knee, or thigh. Arterial emboli
are generally a complication of heart disease. An arterial embolism
in the brain (cerebral embolism) causes stroke, which can be fatal.
An estimated 5–14% of all strokes are caused by cerebral emboli.
Arterial emboli to the extremities can lead to tissue death, and
amputation of the affected limb if not treated effectively within
hours. Intestines and kidneys can also suffer damage from emboli.
Gas embolism
Gas emboli result from the compression of respiratory gases into the
blood and other tissues due to rapid changes in environmental
pressure, for example, while flying or scuba diving. As external
pressure decreases, gases (like nitrogen) which are dissolved in the
blood and other tissues become small bubbles that can block blood
flow and cause organ damage.
Pulmonary embolism
In a pulmonary embolism, a common illness, blood flow is blocked at
a pulmonary artery. When emboli block the main pulmonary artery, and
in cases where there are no initial symptoms, a pulmonary embolism
can quickly become fatal. According to the American Heart
Association, an estimated 600,000 Americans develop pulmonary emboli
annually and 60,000 die from it.
A pulmonary embolism is difficult to diagnose. Less than 10% of
patients who die from a pulmonary embolism were diagnosed with the
condition. More than 90% of cases of pulmonary emboli are
complications of deep vein thrombosis, blood clots in the deep vein
of the leg or pelvis. |
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