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Diagnostic
Procedures
Physical Exam
During a medical exam
for suspected endometriosis, the doctor, usually a gynecologist,
will take a careful history of symptoms the patient has experienced
in the past and now. She will usually perform a bimanual pelvic
examination, feeling the pelvic organs through the walls of the
vagina and rectum, and visually inspecting the cervix through a
speculum. She may order blood tests, ultrasound examinations or
other tests.
There is
no simple test that can diagnose endo. An experienced gynecologist
may be able to feel endometriosis nodules during a pelvic exam,
especially in women with more severe disease, but mild to moderate
endometriosis is easily missed during a pelvic exam. Symptoms may
suggest that a patient has endometriosis, but they are not
absolutely indicative of the disease.
Having a first-degree female relative (mother, sister or daughter)
with endometriosis increases the likelihood that a woman with
suspicious symptoms has endometriosis.
Laparoscopy
The only sure way to
diagnose endometriosis is through a minor surgical procedure called
laparoscopy. Diagnostic laparoscopy is generally performed as an
outpatient surgery. The patient is given a general anesthetic, the
abdomen is distended with carbon-dioxide gas to make the organs
easier to see, and an instrument called a laparoscope is inserted
through a small incision in the lower abdomen. For a diagnostic
laparoscopy there may be up to three very small incisions - one in
the navel, and others along the "bikini line" along the lower
abdomen.
The laparoscope is a
lighted instrument with a magnifying lens that the surgeon looks
through directly. More common is the video laparoscope, where the
magnified view from inside the abdomen is displayed on a large video
monitor in the operating room. Both types of laparoscope can show
the tissue from normal to six-times actual size. It enables the
surgeon to see around the organs and carefully inspect for signs of
endometriosis or other abnormalities.
During
laparoscopy the surgeon can see the extent, size, and location of
endometriosis lesions and scarring. Biopsies can be taken during the
procedure. Often the diagnostic procedure extends into a therapeutic
"operative laparoscopy" where the surgeon uses a laser,
electrosurgery and sharp instruments to remove as much endometriosis
as possible. This is discussed in greater detail in the section on
surgical treatment of endometriosis.
MRI
In Europe, magnetic
resonance imaging (MRI) is sometimes used to diagnose endometriosis.
In an MRI, the patient lies very still in a big, tube-shaped
apparatus with magnets circling very fast within the walls of the
tube. MRI gives a very clear, crisp image of the soft tissues of the
body. It takes pictures in "slices", similar to the effect you get
by cutting an orange into many circular slices of different sizes as
you move through the orange.
MRI is not invasive
or painful, but it can be an uncomfortable procedure. The machine is
disturbingly loud, and it can be scary and claustrophobic to be
confined in the tunnel for up to an hour, lying absolutely still
with your limbs weighted down with sand bags or straps to keep you
from moving. On the other hand, if you don't mind the noise, you
might even fall asleep. MRI is an expensive procedure. It is
generally not used for diagnosing endometriosis in the United
States, as most insurance companies refuse to pay for it.
Ultrasound
Ultrasound cannot
diagnose endometriosis, but it can help the doctor to visualize
ovarian cysts and certain abnormalities of the uterus and fallopian
tubes. Almost all ovarian cysts will show up on ultrasound, with
endometriomas ( blood-filled endometriosis cysts) having a typical
"ground glass" appearance.
Ultrasound can be
imaged either through the abdominal wall or through the vagina. In
abdominal ultrasound the patient must have a very full bladder for
the technician to see the pelvic landmarks. The patient lies on a
table and the technician rubs a small, round paddle with conducting
jelly over the patient's abdomen. Trans-vaginal ultrasound can
actually be more comfortable for the patient, as a full bladder is
not necessary. The patient lies on a table with her legs in stirrups
as for a pelvic exam. The technician inserts a condom-covered wand
with conducting jelly into the vagina and gently moves it around to
image the pelvis.
CA-125
A blood test that
checks for the presence of a substance known as CA-125 in the
bloodstream can be indicative of endometriosis, but it is not
diagnostic. CA-125 is elevated in many types of pelvic disease, most
notably in ovarian cancer. It may also be elevated in endometriosis,
pelvic inflammatory disease, fibroids, and other inflammatory
conditions. Because it is not very specific, it is not a very good
tool for diagnosing endometriosis. |