GENITAL HERPES
TREATMENTS |
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There is no cure for herpes virus
infections. There are antiviral drugs available which have some
effect in lessening the symptoms and decreasing the length of herpes
outbreaks. There is evidence that some may also prevent future
outbreaks. These antiviral drugs work by interfering with the
replication of the viruses and are most effective when taken as
early in the infection process as possible. For the best results,
drug treatment should begin during the prodrome stage before
blisters are visible. Depending on the length of the outbreak, drug
treatment could continue for up to 10 days.
Acyclovir (Zovirax) is the drug of choice for herpes infection and
can be given intravenously, taken by mouth (orally), or applied
directly to sores as an ointment. Acyclovir has been in use for many
years and only five out of 100 patients experience side effects.
Side effects of acyclovir treatment include nausea, vomiting, itchy
rash, and hives. Although acyclovir is the recommended drug for
treating herpes infections, other drugs may be used including
famciclovir (Famvir), valacyclovir (Valtrex), vidarabine (Vira-A),
idoxuridine (Herplex Liquifilm, Stoxil), trifluorothymidine (Viroptic),
and penciclovir (Denavir).
Acyclovir is effective in treating both the primary infection and
recurrent outbreaks. When taken intravenously or orally, acyclovir
reduces the healing time, virus shedding period, and duration of
vesicles. The standard oral dose of acyclovir for primary herpes is
200 mg five times daily or 400 mg three times daily for a period of
10 days. Recurrent herpes is treated with the same doses for a
period of five days. Intravenous acyclovir is given to patients who
require hospitalization because of severe primary infections or
herpes complications such as aseptic meningitis or sacral
ganglionitis (inflammation of nerve bundles)
Patients with frequent outbreaks (greater than six to eight per year)
may benefit from long term use of acyclovir which is called "suppressive
therapy." Patients on suppressive therapy have longer periods
between herpes outbreaks. The specific dosage used for suppression
needs to be determined for each patient and should be reevaluated
every few years. Alternatively, patients may use short term
suppressive therapy to lessen the chance of developing an active
infection during special occasions such as weddings or holidays.
There are several things that a patient may do to lessen the pain of
genital sores. Wearing loose fitting clothing and cotton underwear
is helpful. Removing clothing or wearing loose pajamas while at home
may reduce pain. Soaking in a tub of warm water and using a blow
dryer on the "cool" setting to dry the infected area is helpful.
Putting an ice pack on the affected area for 10 minutes, followed by
5 minutes off and then repeating this procedure may relieve pain. A
zinc sulfate ointment may help to heal the sores. Application of a
baking soda compress to sores may be soothing.
Neonatal herpes
Newborn babies with herpes virus infections are treated with
intravenous acyclovir or vidarabine for 10 days. These drugs have
greatly reduced deaths and increased the number of babies who appear
normal at one year of age. However, because neonatal herpes
infection is so serious, even with treatment babies may not survive,
or may suffer nervous system damage. Infected babies may be treated
with long term suppressive therapy.
Alternative treatment
An imbalance in the amino acids lysine and arginine is thought to be
one contributing factor in herpes virus outbreaks. A ratio of lysine
to arginine that is in balance (that is more lysine than arginine is
present) seems to help the immune system work optimally. Thus, a
diet that is rich in lysine may help prevent recurrences of genital
herpes. Foods that contain high levels of lysine include most
vegetables, legumes, fish, turkey, beef, lamb, cheese, and chicken.
Patients may take 500 mg of lysine daily and increase to 1,000 mg
three times a day during an outbreak. Intake of the amino acid
arginine should be reduced. Foods rich in arginine that should be
avoided are chocolate, peanuts, almonds, and other nuts and seeds.
Clinical experience indicates a connection between high stress and
herpes outbreaks. Some patients respond well to stress reduction and
relaxation techniques. Acupressure and massage may relieve tiredness
and stress. Meditation, yoga, tai chi, and hypnotherapy can also
help relieve stress and promote relaxation.
Some herbs, including echinacea (Echinacea spp.) and garlic (Allium
sativum), are believed to strengthen the body's defenses against
viral infections. Red marine algae (family Dumontiaceae), both taken
internally and applied topically, is thought to be effective in
treating herpes type I and type II infections. Other topical
treatments may be helpful in inhibiting the growth of the herpes
virus, in minimizing the damage it causes, or in helping the sores
heal. Zinc sulphate ointment seems to help sores heal and to fight
recurrence. Lithium succinate ointment may interfere with viral
replication. An ointment made with glycyrrhizinic acid, a component
of licorice (Glycyrrhiza glabra), seems to inactivate the virus.
Topical applications of vitamin E or tea tree oil (Melaleuca spp.)
help dry up herpes sores. Specific combinations of homeopathic
remedies may also be helpful treatments for genital herpes. |
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