Specific diagnostic tests used depend on the
location of the cancer. The standard tests are:
Physical examination
The first step in diagnosis is a complete and
thorough examination of the oral and nasal cavity, using mirrors and
other visual aids. The tongue and the back of the throat are
examined as well. Any suspicious looking lumps or lesions are
examined with fingers (palpation). In order to look inside the
larynx, the doctor may sometimes perform a procedure known as
laryngoscopy. In indirect laryngoscopy, the doctor looks down the
throat with a small, long handled mirror. Sometimes the doctor
inserts a lighted tube (laryngoscope or a fiberoptic scope) through
the patient's nose or mouth. As the tube goes down the throat, the
doctor can observe areas that cannot be seen by a simple mirror.
This procedure is called a direct laryngoscopy. Sometimes patients
may be given a mild sedative to help them relax, and a local
anesthetic to ease any discomfort.
Blood tests
The doctor may order blood or other immunological
tests. These tests are aimed at detecting antibodies to the Epstein-Barr
virus, which has been known to cause cancer of the nasopharynx.
Imaging tests
X rays of the mouth, the sinuses, the skull, and
the chest region may be required. A computed tomography scan (CT
scan), a procedure in which a computer takes a series of x ray
pictures of areas inside the body, may be done. Ultrasonograms (images
generated using sound waves) or an MRI (magnetic resonance imaging)
a procedure in which a picture is created using magnets linked to a
computer), are alternate procedures which a doctor may have done to
get detailed pictures of the areas inside the body.
Biopsy
When a sore does not heal or a suspicious patch
or lump is seen in the mouth, larynx, nasopharynx, or throat, a
biopsy may be performed to rule out the possibility of cancer. The
biopsy is the most definitive diagnostic tool for detecting the
cancer. If cancerous cells are detected in the biopsied sample, the
doctor may perform more extensive tests in order to find whether,
and to where, the cancer may have spread.